X.T.OOI1, E.CHOI2, H.R.HAN1, K.R.PATWARDHAN3, N.S.CHANDRAN3
MOH Holdings Pte Ltd (MOHH)1, National Skin Centre2, National University Hospital3
Hidradenitis Suppurativa (HS) is a chronic debilitating inflammatory disorder of the apocrine gland bearing skin that leads to disfiguring lesions, foul-smelling discharge, scarring and pain. Patients with HS often report psychological symptoms and impaired quality of life (QoL). Our study aims to comprehensively study the impact of HS on patient’s pain, psychosocial health and QoL via validated questionnaires.
We conducted a single-centred retrospective and prospective study in NUH. 41 patients were recruited. Baseline characteristics of each patient were recorded. Disease severity was evaluated with Hurley, Physician Global Assessment (PGA) and modified Satorius (mSatorius) score and impact of HS on patients’ pain was evaluated via Visual Analog Scale (VAS), QOL via Dermatology Life Quality Index (DLQI) and Patient Global Assessment (PtGA), psychological health via Hospital Anxiety and Depression Scale (HADS) and Rosenburg self-esteem scale. We also assessed the impact of the HS on work productivity via WPAI-SHP and school absenteeism with a series of questions.
The mean DLQI score is 6.2 +/- 7.43. Higher disease severity scores (Hurley and PGA) is significantly associated with higher pain score as assessed by VAS (Hurley p0.002, PGA p<0.001), poorer QOL as assessed by DLQI (Hurley p0.004, PGA p<0.001) and PtGA (PGA p<0.001) and more negative psychological impact as assessed by HADS (Hurley p 0.002, PGA p0.001). There is no correlation between disease severity and work/school absenteeism.
Severe disease in HS causes increase pain, poorer QOL and higher psychological burden. This emphasizes the importance of early detection, prompt intervention and prevention of disease progression.