SHBC1081

H.P.PHUA¹, W.Y.LIM¹, G. GANESAN², J YOONG³, K.B.TAN², J.A. ABISHEGANADEN¹, A.Y.H. LIM¹

Tan Tock Seng Hospital¹, Ministry of Health², Center for Economic and Social Research³

Little is known about the epidemiology of bronchiectasis in Asia. This study describes the disease burden of bronchiectasis in Singapore.

A nationwide administrative dataset was used to identify hospitalizations with bronchiectasis as a diagnosis. Population statistics and medical encounter data were used to estimate the incidence, prevalence and hospitalizations associated with hospitalization-requiring bronchiectasis.

There were 420 incident hospitalized bronchiectasis patients in 2017, giving an incidence rate of 10.6/100,000. Age-standardized incidence declined on average by 2.7% per year between 2007 and 2017. Age-standardized incidence rates of hospitalization-requiring bronchiectasis in women are also starting to exceed those in men. Incidence rates increased strongly with age in both men and women. Tuberculosis was a secondary diagnosis in 37.5% of incident hospitalizations in 2007, but has declined sharply since then. Patient survival was considerably lower in both men (5-year Relative Survival Ratios (RSR) of 0.63 (95% CI, 0.59 to 0.66)) and women ((5-year RSR of 0.75 (95% CI, 0.72 to 0.78)). The point prevalence of bronchiectasis was 147.1/100,000 in 2017, and increased sharply with age, with more than 1% of people aged 75 years and older having bronchiectasis. In 2017, there were a total of 1,105 hospitalization episodes with bronchiectasis as a primary diagnosis, which accounted for 0.2% of total acute hospitalisations and 0.3% of total acute inpatient bed-days in 2017.

Bronchiectasis is common and imposes a substantial burden on health care utilization and survival rates of patients in Singapore.